With the Ultra X, we recommend using 10% of the dosage for at least the first week or until such a time as the eyes have acclimatised to the product. In practice this is one drop per eye, per day (when using as a drop) or one drop per eye and one drop on each mask pad, per day (when using with AMEYEZ). This gives the eyes plenty of time to adjust to our strongest formula. After one week you can work your way up to the full dosage (increasing by 20% everyday).